Hygeia's signature O3UV therapy combines medical ozone with ultraviolet light in one advanced blood-based therapy. Led by Holly Deffert, RN, each treatment is personalized to your individual wellness goals, with options ranging from foundational ozone support to high-dose O3UV protocols.
Advanced therapy. Personalized care. A deeper approach to cellular wellness.
If you have been tired and inflamed for a long time, and your labs keep coming back "normal" while you still feel unwell, you are describing the person ozone therapy was made for.
Conventional visits often end with reassurance instead of answers. O3UV is used by integrative practitioners to support cellular oxygen use, circulation, and immune function, so your body has more of what it needs to recover.
Most people who find Hygeia are not looking for a quick fix. They are proactive women and men, often in their 40s, 50s, and 60s, who want to age well, recover faster, and feel like themselves again. Some arrive after years of being dismissed; others are healthy and want to stay that way. Holly works with clients across the full spectrum, from everyday people to athletes, because lasting change comes from commitment over time, not a single appointment.
Before any treatment, she takes time to understand your history, your goals, and whether ozone is genuinely a good fit. What we can promise is honest guidance, careful technique, and a plan built around your terrain rather than a one-size-fits-all protocol. If that is the kind of partnership you have been looking for in the Denver foothills, this is a good place to start.
Ozone therapy is not FDA-approved to diagnose, treat, or cure any disease, and results vary from person to person.
O3UV combines medical ozone with ultraviolet blood irradiation (UVBI) in one blood-based therapy.
During treatment, a measured amount of blood is drawn into a closed system, where it is exposed to a carefully controlled concentration of medical ozone and specific wavelengths of ultraviolet light before being returned to your circulation.
Medical ozone and ultraviolet blood irradiation have each been studied independently for their effects on oxidative signaling, cellular processes, and immune response. O3UV brings these two modalities together in a single treatment.
At Hygeia, your protocol is individualized based on your health history, goals, and overall wellness plan.
Think of O3UV as cellular support-not a cure or a one-size-fits-all treatment.
Hygeia offers a full range of ozone modalities so your plan can be matched to your goals and budget, rather than forcing one approach on everyone. Each option below is administered by Holly Deffert, RN, with transparent pricing and clear time expectations. Many clients combine ozone with UV light because the pairing is the foundation of our signature O3UV service.
This is the combination we recommend for most people: ozonated blood passed through UVA, UVB, and UVC light, then reinfused. VIP member rates and multi-session packages are available. Drip time is 20 to 30 minutes, with the full visit up to an hour.
A higher-dose protocol popular in Europe, delivering about 70,000 micrograms of ozone with two passes of UV light. The SOPMed-pioneered approach draws less blood than the traditional German "10-pass" method while still including the ultraviolet step that many standard protocols skip. VIP member rates and packages are available. We recommend titrating up to high-dose rather than starting there.
Minor Autohemotherapy, insufflations, and joint therapy round out the menu for targeted, lower-cost, or at-home support. Insufflation kits start at $50, and ozone joint therapy is priced by treatment area beginning at $250.
Every modality has a best-fit situation. Holly will help you choose rather than guessing on your own.
Your O3UV experience begins with a brief check-in so we can review how you're feeling and determine the appropriate protocol for you.
During treatment, blood is drawn into a closed system, exposed to a precise concentration of medical ozone and ultraviolet light, and then returned to your circulation. Depending on your individualized protocol, treatment volume and appointment length may vary.
Most clients simply relax, read, work, or rest during their session.
O3UV may be used as a single wellness treatment or as part of a personalized series. Some clients choose a more concentrated series, while others incorporate O3UV into an ongoing wellness or longevity routine.
There is no one-size-fits-all schedule. Your frequency and protocol are based on your goals, health history, response to therapy, and overall wellness plan.
At Hygeia, the focus is always on safety, comfort, education, and individualized care, so you understand what we're doing and why we're doing it.
At Hygeia, your care is personal from beginning to end. Holly Deffert, RN, personally performs your O3UV treatments, giving you consistency with someone who knows your history, your goals, and how you've responded along the way.
With 14 years of emergency nursing experience and a passion for integrative and regenerative wellness, Holly brings clinical experience together with a deeply individualized approach to care.
O3UV can stand alone or become part of a bigger wellness strategy incorporating advanced testing, IV therapies, nutrition, detoxification support, and regenerative medicine when appropriate.
Located in the Denver foothills, Hygeia serves Idledale, Evergreen, Morrison, Golden, Conifer, Genesee, and surrounding communities.
No assembly-line wellness. No one-size-fits-all protocols. Just thoughtful, personalized care and a plan built around you.
Prepaid sets built to bring the per-session cost down when you commit to a series.
Packages are prepaid and personalized during your consult. Savings shown are against single-session pricing.
Ozone therapy uses medical-grade ozone, a highly active form of oxygen, in precise therapeutic doses to support the body's oxygen use, circulation, and natural defenses. At Hygeia it is most often delivered intravenously as Major Autohemotherapy, where a small amount of blood is ozonated and reinfused. It is used by integrative practitioners worldwide and is not FDA-approved to treat or cure disease.
Major Autohemotherapy (MAH) ozonates your blood and returns it to circulation. O3UV adds a second step, passing that blood through UVA, UVB, and UVC light before reinfusion. O3UV is our signature service because research suggests ozone and ultraviolet light may work more effectively together. O3UV sessions are $350, with VIP member rates and package pricing available.
Many people seek ozone therapy to support circulation, tissue oxygenation, and the body's natural healing processes, and Holly has worked with clients facing difficult wounds. Whether ozone is appropriate depends entirely on the individual, so the first step is always a consultation, not a booking. Holly will review the situation honestly and coordinate with other providers when that serves the person best.
When administered correctly with medical-grade equipment and precise dosing, ozone therapy is generally well tolerated, which is why Holly, an RN, performs every treatment personally. As with any therapy, some people experience temporary effects, and ozone is not appropriate for everyone. A consultation lets Holly review your health history and confirm whether treatment is safe and suitable for you before anything begins.
Ozone therapy is not approved by the FDA to diagnose, prevent, treat, or cure any disease, and we state that plainly. It is used by integrative and holistic practitioners around the world to support general wellness, and research is ongoing. Hygeia offers it as an alternative wellness option, with honest expectations and individualized guidance rather than promises of specific medical outcomes.
Pricing depends on the modality. O3UV is $350 per session and HiDose O3UV is $750, each with reduced VIP-member rates and multi-session packages that lower the per-visit cost. Minor autohemotherapy, insufflations, and joint therapy are lower-cost options. Holly recommends a package and a plan during your consultation so the investment matches your goals.
Expect a clarity call first, then a tailored plan, usually a package of five to ten O3UV sessions at one to two per week, followed by a maintenance rhythm. Holly builds up dosing gradually, combines ozone with UV light as our signature approach, and adjusts as your body responds. Many foothills clients continue maintenance for prevention long after their first concern resolves.
Holly Deffert is a registered nurse with 14 years of emergency medicine experience and the founder of Hygeia Wellness in Idledale, Colorado.
Her practice focuses on medical ozone and O3UV therapy, regenerative medicine and stem cell therapies, NAD+, advanced IV therapies, cellular health, and longevity.
Holly personally works with each client, combining her clinical background with a research-informed, root-cause approach to create individualized wellness strategies. She also collaborates with naturopathic, functional-medicine, and holistic providers when appropriate to support the bigger picture of each client's health.
Personalized care. Advanced wellness. A nurse who takes the time to look deeper.
O3UV at Hygeia combines medical ozone + ultraviolet light with personalized, nurse-led care designed around you.
Whether you're looking for greater vitality, recovery support, cellular wellness, or a more proactive approach to longevity, we'll help you determine whether O3UV belongs in your personalized wellness plan.
Your health is an investment. Your wellness is a choice.
Start with a complimentary clarity call with Holly, no pressure, just a conversation about where you are and where you want to go.
